The best fertility clinics in Minnesota are not necessarily the clinics with the highest single success-rate percentage.

The right choice depends on the treatment you need, the clinic’s laboratory and IVF experience, your location and, if you’re considering surrogacy, how often the clinic works with gestational carriers.

Most of Minnesota’s major fertility programs are concentrated in the Twin Cities and Rochester. Intended parents in Minneapolis, St. Paul and nearby suburbs have several options within the metro, while families in northern, western and rural Minnesota may need to plan for longer drives or ask whether some monitoring can be completed closer to home.

This guide compares four Minnesota fertility clinics using the 2024 SART data supplied for this article.

It also explains how to interpret success rates, compare costs and evaluate whether a clinic is equipped to support both IVF and a future gestational surrogacy case.

Fertility Clinics in Minnesota

Minnesota intended parents have several established SART member clinics to compare, including programs in Edina, Minneapolis, Woodbury and Rochester.

The Society for Assisted Reproductive Technology is the primary U.S. professional organization focused on assisted reproductive technology and represents most ART clinics nationwide. Its clinic reports give intended parents a standardized way to review treatment outcomes, services and other clinic information.

Four programs to compare when researching the best fertility clinics in Minnesota are:

• CCRM Minneapolis (Edina)
• Mayo Clinic Assisted Reproductive Technologies (Rochester)
• Center for Reproductive Medicine (Minneapolis)
• Reproductive Medicine and Infertility Associates, or RMIA (Woodbury)

The clinics featured in this guide are SART member clinics with verified laboratory accreditation. Unless otherwise noted, the success-rate figures below are based on the 2024 SART data provided for this article.

CCRM Minneapolis

Location: 6565 France Avenue South, Suite 400A, Edina, MN 55435
Phone: (952) 225-1630

CCRM Minneapolis is an Edina fertility clinic with services including:

• Donor egg
• Donor embryo
• Egg cryopreservation
• Embryo cryopreservation
• Female couple family building
• HIV patients
• Male couple family building
• Mental health
• Outside monitoring
• PGT

Its location southwest of Minneapolis may be convenient for intended parents in Minneapolis and the western or southern Twin Cities suburbs.

Transfer Type	Under 35	35–37	38–40	41–42	Over 42
2024 Frozen Embryo Transfer With PGT-A	65%	61.5%	65%	68.6%	12/18
2024 Frozen Embryo Transfer Without PGT-A	58.8%	8/13	2/4	0/2	0/0

Some age groups are reported as fractions because relatively few transfers occurred.

If CCRM is on your shortlist, ask how many transfers sit behind the result most relevant to your age and treatment plan.

Mayo Clinic Assisted Reproductive Technologies

Location: Eisenberg 2A, 200 First Street S.W., Rochester, MN 55905
Phone: (507) 284-9792

Mayo Clinic Assisted Reproductive Technologies gives intended parents in southeastern Minnesota a major fertility program outside the Twin Cities. Its Rochester location may reduce travel for families in that part of the state.

The Mayo Clinic fertility program offers IVF and related reproductive services, including:

• Donor egg
• Donor embryo
• Gestational carriers
• Egg cryopreservation
• Embryo cryopreservation
• Female couple family building
• HIV patients
• Male couple family building
• Mental health
• Outside monitoring
• Ovarian tissue cryopreservation
• PGT

Transfer Type	Under 35	35–37	38–40	41–42	Over 42
2024 Frozen Embryo Transfer With PGT-A	42.1%	41.9%	38.7%	5/10	1/1
2024 Frozen Embryo Transfer Without PGT-A	35.8%	34.8%	24.1%	3/7	2/6

The small sample sizes in several older age groups are important when reading these results.

For example, 1/1 records one live birth from one transfer, not a broad prediction of future outcomes for patients over 42.

Center for Reproductive Medicine

Location: 2828 Chicago Avenue South, Suite 400, Minneapolis, MN 55407
Phone: (612) 863-5390

Center for Reproductive Medicine is a Minneapolis fertility clinic offering:

• Donor egg
• Donor embryo
• Gestational carriers
• Egg cryopreservation
• Embryo cryopreservation
• Female couple family building
• Male couple family building
• Mental health
• PGT

Its location gives intended parents in Minneapolis, St. Paul and nearby communities another option within the central Twin Cities area.

Transfer Type	Under 35	35–37	38–40	41–42	Over 42
2024 Frozen Embryo Transfer With PGT-A	55.4%	47.3%	51.3%	57.9%	5/13
2024 Frozen Embryo Transfer Without PGT-A	49.3%	43.2%	31%	1/3	0/2

When comparing these results with another Minnesota clinic, use the age group and treatment type closest to the care your physician expects to recommend.

An overall clinic percentage can obscure differences between treatment groups.

Reproductive Medicine and Infertility Associates (RMIA)

Location: Woodbury Medical Arts Building, 2101 Woodwinds Drive, Suite 100, Woodbury, MN 55125
Phone: 651-222-6050

RMIA is a Woodbury fertility clinic offering IVF and related services, including treatment involving:

• Donor egg
• Donor embryo
• Gestational carriers
• Egg cryopreservation
• Embryo cryopreservation
• Female couple family building
• Male couple family building
• PGT

Its eastern Twin Cities location may be convenient for intended parents in St. Paul, the eastern suburbs and communities near the Minnesota-Wisconsin border.

Transfer Type	Under 35	35–37	38–40	41–42	Over 42
2024 Frozen Embryo Transfer With PGT-A	57.3%	64.2%	50.6%	4/13	6/9
2024 Frozen Embryo Transfer Without PGT-A	49.6%	48.3%	7/17	3/4	0/0

Several RMIA categories also contain relatively few transfers.

If one of those groups applies to you, ask how many comparable patients the clinic treats and whether more recent internal results differ from the published 2024 figures.

How to Compare Fertility Clinic Success Rates

Fertility clinic success rates are most useful when you compare the same treatment, age group and outcome.

A pregnancy rate from one clinic, for example, isn’t equivalent to a live birth rate from another.

A live birth rate measures whether treatment ultimately resulted in a live birth. It gives intended parents a more complete treatment outcome than a pregnancy rate, which measures an earlier point in the process.

SART explains that age, diagnosis, treatment choices and differences in clinic patient populations can affect reported outcomes.

Its guidance on fertility clinic success rates provides useful context for reading clinic reports rather than treating a single percentage as a ranking.

Treatment volume provides additional context.

 A 60% live birth rate based on hundreds of transfers carries more information than the same percentage based on five transfers.

When reviewing a clinic’s numbers, compare:

• Age at egg retrieval
• Whether PGT-A was used
• Fresh versus frozen transfer
• Single versus multiple embryo transfer
• Use of donor eggs or embryos
• Number of transfers represented
• The clinic’s overall treatment volume
• Whether the patients represented in the data resemble your treatment situation

A clinic with the highest percentage in one category may not have the strongest results for your age group or proposed treatment.

Ask which SART category most closely reflects your situation and how many transfers produced that result.

Understanding the IVF Process

IVF involves stimulating the ovaries, retrieving eggs, fertilizing them in a laboratory and developing embryos for a fresh or future transfer. For intended parents considering gestational surrogacy, those embryos are created before one is transferred to a gestational surrogate.

The Cleveland Clinic IVF overview explains the medical stages involved in an IVF cycle and provides useful context for the treatment data reported by fertility clinics.

The process generally includes:

• Fertility evaluation: Your reproductive endocrinologist reviews your medical and reproductive history and orders testing needed to develop a treatment plan.
• Ovarian stimulation: Injectable hormone medications encourage multiple eggs to mature during one treatment cycle. Ultrasounds and bloodwork monitor the response.
• Egg retrieval: When the eggs are ready, a fertility specialist retrieves them in an ultrasound-guided procedure.
• Fertilization and embryo development: Mature eggs are fertilized with sperm in the embryology laboratory. The embryos are then monitored as they develop.
• Optional preimplantation genetic testing: Depending on your circumstances, embryos may undergo PGT-A to screen for chromosome abnormalities or PGT-M when testing for a specific single-gene condition is appropriate.
• Embryo cryopreservation: Embryos can be frozen for a future transfer. In gestational surrogacy, embryos are often already stored while the surrogate completes screening, medical clearance and the legal-contract process.

The clinic’s laboratory plays a role well before embryo transfer.

Ask where fertilization, embryo culture, genetic-testing biopsy, freezing and storage take place, particularly if any of those services are performed outside the clinic.

Average IVF Costs in Minnesota

IVF costs in Minnesota commonly fall in the range of roughly $15,000 to $30,000 when medications are included, although the amount can vary substantially based on the clinic and treatment plan.

Your total cost may include:

• Fertility evaluation and monitoring
• Ovarian stimulation medications
• Egg retrieval
• Anesthesia
• Fertilization and laboratory fees
• ICSI, if recommended
• Embryo freezing
• PGT-A or PGT-M, if selected
• Donor eggs, if needed
• Donor sperm, if needed
• Embryo storage
• Frozen embryo transfer

The Minnesota IVF cost guide from CNY Fertility provides state-specific cost context and shows how medications and additional services can change the amount paid beyond a clinic’s base IVF fee.

Insurance can change the out-of-pocket total substantially.

Minnesota does not currently have a broad statewide requirement that private health plans cover infertility treatment. Some employer-sponsored and public employee plans may provide fertility benefits, so coverage depends in part on the individual policy.

Before comparing two clinics by price, ask for a written estimate showing what’s included and what’s billed separately. Then confirm coverage for the physician, clinic, laboratory, medications and procedures with your insurer.

For families in Greater Minnesota, treatment expenses can also include repeated travel to Minneapolis, Edina, Woodbury or Rochester.

Ask whether routine ultrasounds and bloodwork can be handled through outside monitoring closer to home.

Questions to Ask Before Choosing a Fertility Clinic

The most useful questions to ask at a fertility clinic consultation reveal how the clinic performs with patients like you, what your treatment would involve and which services could affect your total cost.

• “What is your live birth rate for my age group and treatment type?” This gives you a more relevant result than the clinic’s overall success rate.
• “How many IVF cycles do you perform each year?” Treatment volume helps put published percentages into context.
• “How often do you perform gestational carrier transfers?” If you’re planning surrogacy, this tells you whether gestational carrier cases are a routine part of the clinic’s work.
• “Do you have an on-site embryology lab?” Ask where fertilization, embryo culture, biopsy, freezing and storage take place.
• “Which treatments or services increase the quoted cost?” Ask specifically about medications, anesthesia, ICSI, PGT, freezing, storage and future transfers.
• “What happens if my first IVF cycle isn’t successful?” The answer can show how the physician uses the results of one cycle to shape the next treatment plan.
• “Will you accept embryos created at another fertility clinic?” This matters if you already have frozen embryos or may transfer care later.
• “How do you coordinate with surrogacy agencies and reproductive attorneys?” A clinic accustomed to gestational carrier cases should be able to explain its medical- and legal-clearance process.
• “Which appointments will my gestational surrogate need to attend in person?” This helps you anticipate travel requirements before matching.

For intended parents in rural Minnesota, access may be as important as distance to the clinic itself. Ask whether bloodwork and ultrasounds can be completed closer to home and sent to your treating clinic.

Insurance deserves its own question during the consultation. Confirm whether the clinic and embryology laboratory participate in your insurance network and which parts of an IVF cycle require prior authorization or remain self-pay.

How Fertility Clinics Work with Surrogacy Agencies

Fertility clinics and surrogacy agencies handle different parts of a gestational surrogacy case.

The clinic manages reproductive medical care, while the agency generally handles matching, screening coordination, case management, travel logistics and other non-medical parts of the process.

Understanding the roles of surrogacy agencies and clinics can help you identify which professional should handle each part of the process.

When you’re choosing a fertility clinic for surrogacy, look closely at its gestational carrier screening requirements, transfer experience and procedures for communicating with agencies and reproductive attorneys.

It’s also useful to ask how the clinic coordinates care when the gestational surrogate lives outside Minnesota.

After embryos have been created, the medical and agency sides of a typical gestational surrogacy case generally come together this way:

1. You choose a gestational surrogate. The surrogacy agency facilitates the match according to its matching and screening process.
2. The fertility clinic reviews her medical records. The clinic determines whether she can proceed with its medical screening requirements.
3. The surrogate completes medical clearance. She travels to the intended parents’ fertility clinic when the clinic requires an in-person screening appointment.
4. Legal contracts are completed. The intended parents and surrogate work with their respective reproductive attorneys to complete the Gestational Carrier Agreement before the clinic proceeds with transfer.
5. The fertility clinic performs the embryo transfer. The surrogate follows the clinic’s medication and monitoring protocol and travels to the clinic for the transfer.
6. The fertility clinic monitors the early pregnancy. After the clinic’s early-pregnancy monitoring period, the surrogate transitions to her obstetric provider for prenatal care.

Your surrogate doesn’t necessarily need to live near your Minnesota clinic. She may live elsewhere in Minnesota or in another state and travel to the clinic for required screening and embryo transfer appointments.

With an agency-assisted journey, the agency generally coordinates required surrogate travel and scheduling.

Eligible travel expenses are typically addressed through the program’s expense and compensation structure, although the exact policy varies by agency.

Talk With a Surrogacy Professional About Choosing the Right Fertility Clinic

If surrogacy is part of your plan, your fertility clinic needs to support both your IVF treatment and the medical requirements of a future gestational surrogate.

Compare the clinic’s laboratory services, costs, location and experience with gestational carrier cases alongside its success-rate data.

A surrogacy professional can help you understand how those clinic requirements fit into the larger process. We  can connect you with a surrogacy professional to discuss IVF, gestational carrier requirements and provider coordination.

Choose a clinic based on the care your treatment requires and how well it can work with the professionals involved in your surrogacy plan.